The practice of vaccination against disease began in 1796 by Edward Jenner, who used the pus of blisters from cowpox to vaccinate people against smallpox. Despite the fact that vaccination is perhaps viewed as the strongest preventive measure against disease in modern health care, its practice and protocol has been challenged in recent years by a growing number of doctors and scientists, as well as a large number of parents. Recent immunology research and the availability of health information have caused the challenge of the foundational tenets of vaccination. “The control or even eradication of childhood disease has been heralded as one of medicine’s finest accomplishments, yet there is a growing suspicion that infection intervention may have an adverse effect on the patients. As childhood infections have decreased, chronic afflictions have increased.